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印度天门冬(沙塔瓦里)对正常健康志愿者胃排空时间的影响。

Effect of Asparagus racemosus (Shatavari) on gastric emptying time in normal healthy volunteers.

作者信息

Dalvi S S, Nadkarni P M, Gupta K C

机构信息

Department of Pharmacology, Seth G. S. Medical College, Bombay, Maharashtra.

出版信息

J Postgrad Med. 1990 Apr;36(2):91-4.

PMID:2097375
Abstract

Asparagus racemosus (Shatavari) is used in Ayurveda for dyspepsia (amlapitta) and as a galactogogue. It was hence compared with a modern drug, metoclopramide, which is used in dyspepsia to reduce gastric emptying time. Gastric emptying half- time (GE t1/2) was studied in 8 healthy male volunteers using a cross-over design. The basal GE t1/2 in volunteers was 159.9 +/- 45.9 min (mean +/- SD) which was reduced to 101 +/- 40.8 min by Shatavari (p less than 0.001) and to 85.3 +/- 21.9 by metoclopramide (p less than 0.001). Metoclopramide and Shatavari did not differ significantly in their effects.

摘要

阿育吠陀医学中使用印度人参(Shatavari)治疗消化不良(胃酸过多)并作为催乳剂。因此,将其与现代药物甲氧氯普胺进行了比较,甲氧氯普胺用于治疗消化不良以缩短胃排空时间。采用交叉设计在8名健康男性志愿者中研究了胃排空半衰期(GE t1/2)。志愿者的基础GE t1/2为159.9 +/- 45.9分钟(平均值 +/- 标准差),印度人参将其缩短至101 +/- 40.8分钟(p < 0.001),甲氧氯普胺将其缩短至85.3 +/- 21.9分钟(p < 0.001)。甲氧氯普胺和印度人参的效果无显著差异。

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Chemical analysis reveals the botanical origin of shatavari products and confirms the absence of alkaloid asparagamine A in Asparagus racemosus.化学分析揭示了雪蛤产品的植物来源,并证实了天门冬酰胺 A 在天门冬属植物中的不存在。
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