Levien A S, Summers B A, Szladovits B, Benigni L, Baines S J
Department of Veterinary Clinical Sciences, The Royal Veterinary College, North Mymms, Hatfield, Hertfordshire AL9 7TA.
J Small Anim Pract. 2010 Nov;51(11):604-8. doi: 10.1111/j.1748-5827.2010.01006.x.
A 9-year-old, female neutered Dalmatian was evaluated for acute onset of dyspnoea. Thoracocentesis on presentation yielded 1300 ml sanguineous fluid, while thoracic radiology and ultrasonography showed a mixed-echoic cavitary cranial mediastinal mass, sternal lymph node enlargement and pleural effusion. Surgical exploration of the thorax revealed a multi-lobulated red/brown cranial mediastinal mass and multiple similarly coloured ovoid nodules within several lung lobes. Histopathology revealed thymic branchial cysts with neoplastic transformation and examination of the lung was consistent with metastasis. Despite initially recovering well, acute sepsis and pyothorax resulted in cardiac arrest 8 days postoperatively. This is the first veterinary report of neoplastic transformation of a thymic branchial cyst with pulmonary metastasis.
一只9岁已绝育的雌性斑点犬因急性呼吸困难接受评估。就诊时胸腔穿刺抽出1300毫升血性液体，而胸部放射学检查和超声检查显示前纵隔有一个混合回声的空洞性肿块、胸骨旁淋巴结肿大及胸腔积液。胸部手术探查发现前纵隔有一个多叶状的红/褐色肿块，多个肺叶内有多个颜色相似的卵圆形结节。组织病理学检查显示胸腺鳃裂囊肿发生肿瘤转化，肺部检查结果符合转移表现。尽管最初恢复良好，但术后8天急性脓毒症和脓胸导致心脏骤停。这是关于胸腺鳃裂囊肿发生肿瘤转化并伴有肺转移的首例兽医报告。
