Institute of Mental Health Research, University of Ottawa, Ottawa, Canada.
Neurosci Biobehav Rev. 2011 Jan;35(3):903-11. doi: 10.1016/j.neubiorev.2010.10.009. Epub 2010 Oct 23.
Whilst recent neuroimaging studies have identified a series of different brain regions as being involved in empathy, it remains unclear concerning the activation consistence of these brain regions and their specific functional roles. Using MKDA, a whole-brain based quantitative meta-analysis of recent fMRI studies of empathy was performed. This analysis identified the dACC-aMCC-SMA and bilateral anterior insula as being consistently activated in empathy. Hypothesizing that what are here termed affective-perceptual and cognitive-evaluative forms of empathy might be characterized by different activity patterns, the neural activations in these forms of empathy were compared. The dorsal aMCC was demonstrated to be recruited more frequently in the cognitive-evaluative form of empathy, whilst the right anterior insula was found to be involved in the affective-perceptual form of empathy only. The left anterior insula was active in both forms of empathy. It was concluded that the dACC-aMCC-SMA and bilateral insula can be considered as forming a core network in empathy, and that cognitive-evaluative and affective-perceptual empathy can be distinguished at the level of regional activation.
虽然最近的神经影像学研究已经确定了一系列不同的大脑区域与同理心有关，但这些大脑区域的激活一致性及其特定的功能角色仍不清楚。本研究使用 MKDA 对最近的 fMRI 同理心研究进行了全脑定量元分析。该分析确定了 dACC-aMCC-SMA 和双侧前岛叶在同理心方面一致激活。假设这里所说的情感感知和认知评估形式的同理心可能具有不同的活动模式，因此比较了这些同理心形式的神经激活。结果表明，在认知评估形式的同理心中，背侧 aMCC 更频繁地被招募，而右侧前岛叶仅参与情感感知形式的同理心。左侧前岛叶在两种形式的同理心中都有活动。研究得出结论，dACC-aMCC-SMA 和双侧岛叶可以被认为是同理心的核心网络，并且可以在区域激活水平上区分认知评估和情感感知同理心。
