Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A & M University, College Station, TX 77843-4467, USA.
Vet Pathol. 2011 Sep;48(5):1004-7. doi: 10.1177/0300985810386465. Epub 2010 Oct 25.
Small intestinal T-cell lymphoma and mucinous adenocarcinoma are rarely reported in the pig, with most lymphomas being of B-cell origin and only a single report of mucinous adenocarcinoma. Two aged Vietnamese potbellied pigs had concurrent T-cell lymphoma and mucinous adenocarcinoma of the small intestine. The lymphomas formed polypoid masses that projected into the intestinal lumen, whereas the mucinous adenocarcinomas were mural masses that bulged from the serosal surface. Immunohistochemically, neoplastic cells within the lymphomas were positive for CD3 and negative for CD79a. Mucicarmine stain highlighted the abundant cytoplasmic and extracellular mucin in the adenocarcinomas.
猪的小肠 T 细胞淋巴瘤和黏液性腺癌很少见报道，大多数淋巴瘤为 B 细胞起源，仅有一例黏液性腺癌的报道。两头老年越南大肚猪同时患有小肠 T 细胞淋巴瘤和黏液性腺癌。淋巴瘤形成息肉状肿块突入肠腔，而黏液性腺癌则是从浆膜表面向外突出的壁状肿块。免疫组织化学染色显示，淋巴瘤中的肿瘤细胞 CD3 阳性，CD79a 阴性。粘卡红染色突出显示了腺癌中丰富的细胞内和细胞外黏蛋白。
