Valeev A E, Garashchuk O A, Dashkin A N
Neirofiziologiia. 1990;22(6):780-6.
Taurine-activated currents in isolated neurons of the rat cerebellum were studied by voltage and "concentration" clamp methods. They were transmitted by potassium and chloride ions. The dose-response curve with the dissociation constant 2 x 10(-3) mol/l was obtained. The cross-desensitization between taurine and GABA, but not between taurine and glycine was shown. These currents were also blocked by bicucullin and strychnine, but in a different manner.
采用电压钳和“浓度”钳技术研究了大鼠小脑离体神经元中牛磺酸激活电流。这些电流由钾离子和氯离子传导。得到了解离常数为2×10⁻³mol/l的剂量-反应曲线。结果表明，牛磺酸与γ-氨基丁酸之间存在交叉脱敏现象，而牛磺酸与甘氨酸之间不存在交叉脱敏现象。这些电流也被荷包牡丹碱和士的宁阻断，但阻断方式不同。
