Tao Ying, Liu Yang, Friedman Carol, Lussier Yves A
Department of Biomedical Informatics, Columbia University, New York, NY 10032, USA.
Drug Discov Today Biosilico. 2004 Nov;2(6):237-245. doi: 10.1016/S1741-8364(04)02423-0.
Information visualization techniques, which take advantage of the bandwidth of human vision, are powerful tools for organizing and analyzing a large amount of data. In the postgenomic era, information visualization tools are indispensable for biomedical research. This paper aims to present an overview of current applications of information visualization techniques in bioinformatics for visualizing different types of biological data, such as from genomics, proteomics, expression profiling and structural studies. Finally, we discuss the challenges of information visualization in bioinformatics related to dealing with more complex biological information in the emerging fields of systems biology and systems medicine.
信息可视化技术利用人类视觉的带宽,是组织和分析大量数据的强大工具。在后基因组时代,信息可视化工具对于生物医学研究不可或缺。本文旨在概述信息可视化技术在生物信息学中的当前应用,用于可视化不同类型的生物数据,例如来自基因组学、蛋白质组学、表达谱分析和结构研究的数据。最后,我们讨论了生物信息学中信息可视化在应对系统生物学和系统医学等新兴领域中更复杂生物信息方面所面临的挑战。