University of Campinas-UNICAMP, Campinas, SP, Brazil.
Neurourol Urodyn. 2010 Nov;29(8):1410-3. doi: 10.1002/nau.20941.
Evaluate the role of pelvic floor muscle training (PFMT) on the treatment of lower urinary tract dysfunction (LUTD) in multiple sclerosis (MS) patients.
In this randomized controlled trial, twenty seven female patients with a diagnosis of MS and LUTD complaints were randomized, in two groups: Treatment group (GI) (N = 13) and Sham group (GII) (N = 14). Evaluation included urodynamic study, 24-hr Pad testing, three day voiding diary and pelvic floor evaluation according to PERFECT scheme. Intervention was performed twice a week for 12 weeks in both groups. GI intervention consisted of PFMT with assistance of a vaginal perineometer. GII received a sham treatment consisted on the introduction of a perineometer inside the vagina with no contraction required.
At the end of the treatment GI was complaining less about storage and voiding symptoms than GII. Furthermore, differences found between groups were: reduction of pad weight (P = 0.00) (Mean: 87,51 grams initial and 6,03 grams final in GI. 69,46 grams initial and 75,88 grams final in GII), number of pads (P = 0.01) (Mean: 3,61 initial and 2,15 final in GI. 3,42 initial and 3,28 final in GII) and nocturia events (P < 0.00) (Mean: 2,38 initial and 0,46 final in GI. 2,55 initial and 2,47 final in GII) and improvements of muscle power (P = 0.00), endurance (P < 0.00), resistance (P < 0.00) and fast contractions (P < 0.00), domains of PERFECT scheme.
PFMT is an effective approach to treat LUTD in female with MS.
评估盆底肌训练(PFMT)在多发性硬化症(MS)患者治疗下尿路功能障碍(LUTD)中的作用。
在这项随机对照试验中,将 27 名被诊断为 MS 合并 LUTD 症状的女性患者随机分为两组:治疗组(GI)(n=13)和假治疗组(GII)(n=14)。评估包括尿动力学研究、24 小时垫试验、三天排尿日记和根据 PERFECT 方案进行的盆底评估。两组均每周进行两次干预,共 12 周。GI 组的干预措施包括在阴道阴道测压计的辅助下进行 PFMT。GII 组接受的假治疗包括将阴道测压计引入阴道内,但无需收缩。
治疗结束时,GI 组在储存和排尿症状方面的抱怨少于 GII 组。此外,两组之间的差异如下:垫重减少(P=0.00)(GI 组:初始 87.51 克,最终 6.03 克;GII 组:初始 69.46 克,最终 75.88 克)、垫数减少(P=0.01)(GI 组:初始 3.61 个,最终 2.15 个;GII 组:初始 3.42 个,最终 3.28 个)和夜间遗尿事件减少(P<0.00)(GI 组:初始 2.38 个,最终 0.46 个;GII 组:初始 2.55 个,最终 2.47 个),以及肌肉力量(P=0.00)、耐力(P<0.00)、阻力(P<0.00)和快速收缩(P<0.00)等领域的改善,PERFECT 方案。
PFMT 是治疗 MS 女性 LUTD 的有效方法。