Kobzar' A I
Sov Med. 1990(12):14-7.
Blood plasma and red cell membrane levels of polyunsaturated fatty acids were measured by gas chromatography in patients with Stage I essential hypertension, borderline arterial hypertension, functional classes II-IV unstable angina pectoris, and unstable angina. The findings suggest that insufficient linolenic acid level in blood plasma and red cell membranes and, in the majority of cases, elevated concentrations of linoleic acid are among lipid metabolism disorders in cardiovascular patients. This fact permits a conclusion that measurements of blood plasma and red cell membrane levels of polyunsaturated fatty acids may be an additional diagnostic criterion permitting an assessment of the disease severity and elucidation of the pathogenesis of coronary disease and arterial hypertension.
通过气相色谱法测定了I期原发性高血压、临界动脉高血压、II-IV级不稳定型心绞痛和不稳定型心绞痛患者血浆和红细胞膜中多不饱和脂肪酸的水平。研究结果表明，血浆和红细胞膜中亚麻酸水平不足，且在大多数情况下亚油酸浓度升高，是心血管疾病患者脂质代谢紊乱的表现。这一事实使我们可以得出结论，测定血浆和红细胞膜中多不饱和脂肪酸的水平可能是一种额外的诊断标准，有助于评估疾病的严重程度，并阐明冠心病和动脉高血压的发病机制。
