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[人体对急性和慢性高原低氧的适应方面]

[Aspects of acclimatization of the human body to acute and chronic high-altitude hypoxia].

作者信息

Damjanović M M

机构信息

Institut of Aviation Medicine, Yugoslav National Army, Belgrade.

出版信息

Srp Arh Celok Lek. 1990 Jul-Aug;118(7-8):323-8.

PMID:2097785
Abstract

Exposure of human body to high altitude environment initiate reaction which could be result whether of adaptation or of exhaustion. The purpose is to establish the human body environment which enables regeneration of own cells. Therefore, mechanism of reestablishment of prevention and recognition of symptoms and signs of insufficient adaptability on high altitude are of great interest for clinical and other medical investigators. Special position in research refers on cardiovascular system. Results show, according to effect of only one factor-catecholamines, that in course of physical training on high altitude, could be expected, cardiac muscle hypertrophy. It is proved, that under special circumstances catecholamines stimulate synthesis of proteins what enables faster regeneration of the cells. However, under conditions of myocardial ischemia, uncontrolled loading of these patients could lead to deterioration of heart function appearance of cardiac insufficiency.

摘要

人体暴露于高海拔环境会引发反应,这可能是适应或疲惫的结果。目的是建立能够使自身细胞再生的人体环境。因此,重新建立预防机制以及识别高海拔适应性不足的症状和体征,对临床和其他医学研究人员来说具有极大的兴趣。研究中的特殊关注点在于心血管系统。结果表明,仅根据儿茶酚胺这一因素的作用,在高海拔进行体育训练过程中,可能会出现心肌肥大。事实证明,在特殊情况下,儿茶酚胺会刺激蛋白质合成,从而使细胞能够更快再生。然而,在心肌缺血的情况下,这些患者不受控制的负荷可能会导致心脏功能恶化,出现心功能不全。

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