Neĭchev Kh, Ivanovska N, Shirova L, Slavcheva E, Stoianova P, Georgiev D, Abrashev I, Velcheva P, Ianchev I
Acta Microbiol Bulg. 1990;26:19-25.
The stimulating properties of three fractions of a glucomacropeptide consisting of different carbohydrate and peptide components were studied. The phagocytic activity of polymorphonuclears was increased on the 24th hour and of macrophages on the 3rd day after application of the preparations to mice. In vitro fraction 3 stimulates the lysozyme activity and the synthesis of proteins and Clq of the macrophages complement. These properties of the cells are collaborated by the established ultrastructural changes. The different composition of the fractions determines their immunostimulating effect.
研究了由不同碳水化合物和肽成分组成的胰高血糖素样肽的三个组分的刺激特性。将制剂应用于小鼠后，第24小时多形核白细胞的吞噬活性增加，第3天巨噬细胞的吞噬活性增加。在体外，组分3刺激巨噬细胞补体的溶菌酶活性以及蛋白质和Clq的合成。细胞的这些特性与已确定的超微结构变化相关。各组分的不同组成决定了它们的免疫刺激作用。
