Zhukov V G, Teleshov V A, Gukasian I A, Ogarkov V I
Arkh Patol. 1985;47(8):39-45.
Morphology and functional activity of peritoneal macrophages were studied at different intervals after the administration of blastolysin to Wistar rats. Alteration of the macrophage ultrastructure and their functional activity proving the stimulatory effect of the preparation on cells is shown. The signs of stimulation were revealed 30 minutes after the administration of the drug, reached a maximum on the 7th and 14th days and was manifested by structural changes of the cell surface, lysosomal apparatus, mitochondria and by activation of phagocytosis.
在给Wistar大鼠注射溶胚素后的不同时间间隔，研究了腹膜巨噬细胞的形态学和功能活性。结果显示巨噬细胞超微结构及其功能活性的改变证明了该制剂对细胞具有刺激作用。给药30分钟后出现刺激迹象，在第7天和第14天达到最大值，表现为细胞表面、溶酶体装置、线粒体的结构变化以及吞噬作用的激活。
