Department of Pediatrics, Lincoln Medical and Mental Health Center, Bronx, NY/Weill Medical College/Cornell University, NY, USA.
J Perinat Med. 2011 Jan;39(1):71-5. doi: 10.1515/jpm.2010.123. Epub 2010 Oct 27.
Despite widespread prenatal serological screening, the Centers for Disease Control recently reported that from 2005 to 2008, congenital syphilis increased by 23%, many being born to black women in the southern United States. We collected data on the epidemiology of this condition in our institution for the past 18 years (January 1, 1991-December 31, 2008). There has been a marked decrease in the incidence of active infection since the 1990s. Through the 18 years period reviewed, only 21 cases of active neonatal infection were documented among 699 babies who had a positive rapid plasma reagin test. Of these 21 cases, only one was symptomatic. As compared to previous studies, poor prenatal care has still the greatest correlation with active infection. This study might contribute towards the reinforcement of current programs and the formulation of newer strategies towards control and elimination of this condition.
尽管广泛开展了产前血清学筛查，但疾病控制中心最近报告称，从 2005 年至 2008 年，先天性梅毒的发病率增加了 23%，其中许多患者是美国南部的黑人妇女所生。我们在过去 18 年（1991 年 1 月 1 日至 2008 年 12 月 31 日）收集了本机构该病的流行病学数据。自 20 世纪 90 年代以来，活动性感染的发病率显著下降。在回顾的 18 年期间，在 699 例快速血浆反应素试验阳性的婴儿中，仅有 21 例确诊为新生儿活动性感染。在这 21 例中，仅有 1 例有症状。与以往的研究相比，产前保健不佳仍然与活动性感染相关性最大。本研究可能有助于加强当前的控制和消除该病的方案和制定新的策略。
