Mascola L, Pelosi R, Blount J H, Binkin N J, Alexander C E, Cates W
JAMA. 1984 Oct 5;252(13):1719-22. doi: 10.1001/jama.252.13.1719.
A total of 159 cases of early congenital syphilis were reported in the United States during 1982, with Texas reporting 50 cases. We reviewed these Texas cases to identify the most important characteristics on which to focus control efforts. Thirty-eight mothers were 25 years of age or younger; 33 were unmarried. All were from minority groups. No congenital syphilis occurred in whites. Blacks were twice as likely as Hispanics to have an infected infant. Foreign-born Hispanic women were three times more likely to be delivered of an infected child than Hispanics born in the United States. Attendance at prenatal care facilities significantly affected the risk of being delivered of an infected child in both black and Hispanic women; 31 women received no prenatal care. Based on these findings, congenital syphilis in Texas can be reduced primarily through improving prenatal care for high-risk populations and by refining casefinding efforts to control infectious syphilis in the community.
1982年美国共报告了159例早期先天性梅毒病例，其中得克萨斯州报告了50例。我们对得克萨斯州的这些病例进行了回顾，以确定控制工作应重点关注的最重要特征。38名母亲年龄在25岁及以下；33名未婚。她们均来自少数族裔群体。白人中未出现先天性梅毒病例。感染婴儿的黑人数量是西班牙裔的两倍。外国出生的西班牙裔女性生出感染儿童的可能性是在美国出生的西班牙裔女性的三倍。是否前往产前护理机构对黑人和西班牙裔女性生出感染儿童的风险有显著影响；31名女性未接受产前护理。基于这些发现，得克萨斯州的先天性梅毒主要可通过改善对高危人群的产前护理以及加强病例发现工作以控制社区内的传染性梅毒来减少。
