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清创后采用颗粒状松质骨自体移植对感染性骨不连进行一期治疗

[One-stage management of infected nonunion using granulated cancellous bone autografting after debridement].

作者信息

Lu Wei-Ju, Li Bin, Qian Hong-Bo, Zeng Xiao-Feng, Xu Bin, Chen Yong, Bao Ni-Rong, Lu Meng, Zhao Jian-Ning

机构信息

Department of Orthopedics, Nanjing General Hospital of Nanjing Command, Nanjing 210002, China.

出版信息

Zhonghua Yi Xue Za Zhi. 2010 Jun 15;90(23):1609-11.

Abstract

OBJECTIVE

To investigate the curative effect of treating infected nonunion with debridement and granulated cancellous bone autografting in a one-stage procedure.

METHODS

Between 1999 and 2005, 38 cases of infected nonunion were treated with immediate granulated cancellous bone autografting after debridement.

RESULTS

At a mean follow-up of 44 months (range: 12 to 93), 33/38 (86.8%) had an excellent outcome, 5 (13.2%) developed infectious recurrent and/or persistent nonunion (1 case with infectious recurrence and persistent nonunion). Two patients suffered refracture after removing external fixator.

CONCLUSION

The success rate of treating infected nonunion with debridement and granulated cancellous bone autografting in one-stage is high.

摘要

目的

探讨一期清创并自体松质骨颗粒植骨治疗感染性骨不连的疗效。

方法

1999年至2005年期间,对38例感染性骨不连患者在清创后即刻行自体松质骨颗粒植骨治疗。

结果

平均随访44个月(范围:12至93个月),38例中有33例(86.8%)疗效优良,5例(13.2%)发生感染复发和/或持续性骨不连(1例感染复发并持续性骨不连)。2例患者拆除外固定器后发生再骨折。

结论

一期清创并自体松质骨颗粒植骨治疗感染性骨不连的成功率较高。

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