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[经可弯曲支气管镜球囊扩张术治疗149例支气管内膜结核所致气管支气管狭窄的临床价值]

[The clinical value of balloon dilatation through flexible bronchoscope in the management of tracheobronchial stenosis in 149 cases of endobronchial tuberculosis].

作者信息

Ding Wei-min, Wang Jing-ping, Fu Yu, Zhang Jian-ying, Fu Wen-xia, Wang Wen-jie

机构信息

Department of Bronchoscope, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing 101149, China.

出版信息

Zhonghua Jie He He Hu Xi Za Zhi. 2010 Jul;33(7):510-4.

Abstract

OBJECTIVE

To explore the clinical value of balloon dilatation through flexible bronchoscope in the management of tracheobronchial stenosis of endobronchial tuberculosis.

METHODS

From January 2005 to September 2009, 149 cases of tracheobronchial stenosis caused by endobronchial tuberculosis were examined by flexible bronchoscope and treated with balloon dilatation. Changes of the clinical features, atelectasis and airway diameters were observed and evaluated before and after the last treatment and in 12 months.

RESULTS

The airway diameters were immediately enlarged (100%, 149/149) after the procedure, and the clinical symptoms were relieved. The average airway diameter changed from (2.7 ± 1.4) mm before the procedure, to (6.8 ± 2.0) mm, (6.4 ± 1.7) mm and (6.3 ± 2.3) mm immediately, 3 and 12 months after the treatments. Expansion of atelectasis was seen in 92% (34/37) of the cases, and the rate of restenosis was 3.4% (5/146) 12 months after treatment. There were significant differences before and after the treatments in the airway diameters, expansion rate of atelectasis and the general outcome (t = 13.09-20.50, P < 0.01), but there were no differences among measurements immediately, 3 and 12 months after the treatments. The final effective rate was 93.3% (139/149). Severe complications (4.0%, 6/149) were rare in these patients.

CONCLUSION

Balloon dilatation through flexible bronchoscope is a simple, effective and safe method for the management of tracheobronchial stenosis after endobronchial tuberculosis.

摘要

目的

探讨经可弯曲支气管镜球囊扩张术治疗支气管内膜结核所致气管支气管狭窄的临床价值。

方法

选取2005年1月至2009年9月因支气管内膜结核导致气管支气管狭窄的149例患者,行可弯曲支气管镜检查并进行球囊扩张术治疗。观察并评估末次治疗前、末次治疗后即刻、治疗后3个月及12个月时的临床特征、肺不张及气道直径变化。

结果

术后气道直径即刻增大(100%,149/149),临床症状缓解。术前平均气道直径为(2.7±1.4)mm,治疗后即刻、3个月及12个月时分别为(6.8±2.0)mm、(6.4±1.7)mm和(6.3±2.3)mm。92%(34/37)的病例肺不张得到改善,治疗后12个月再狭窄率为3.4%(5/146)。治疗前后气道直径、肺不张改善率及总体疗效比较,差异有统计学意义(t=13.09-20.50,P<0.01),但治疗后即刻、3个月及12个月时各项指标比较差异无统计学意义。最终有效率为93.3%(139/149)。这些患者中严重并发症少见(4.0%,6/149)。

结论

经可弯曲支气管镜球囊扩张术是治疗支气管内膜结核后气管支气管狭窄的一种简单、有效且安全的方法。

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