Department of Stroke Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki-City, Okayama, Japan.
Cerebrovasc Dis. 2011;31(1):51-6. doi: 10.1159/000320854. Epub 2010 Oct 28.
Our aim was to confirm the utility of paramedics using the Kurashiki Prehospital Stroke Scale (KPSS), with a maximum score of 13, for patients who may be eligible for administration of intravenous tissue plasminogen activator (IV t-PA).
The subjects comprised acute stroke and transient ischemic attack (TIA) patients transferred to our hospital by paramedics. We analyzed correlations between KPSS and the National Institutes of Health Stroke Scale (NIHSS). Patients admitted within 3 h of onset were categorized into 2 groups: KPSS ≥4 and KPSS <4. We compared the proportion of patients receiving IV t-PA between the groups.
Among 430 consecutive patients (mean age = 73 years; 266 men), paramedics recorded KPSS for 256 patients (59.5%). Excellent correlation was observed between KPSS and NIHSS in all 256 patients (R = 0.766; p < 0.001) and in 94 patients (ischemic stroke and TIA with symptoms on admission) admitted within 3 h of onset (R = 0.706; p < 0.001). Among these 94 patients, IV t-PA was more frequently given in the KPSS ≥4 group (30 of 58 patients, 51.7%) than in the KPSS <4 group (5 of 36 patients, 13.9%; p < 0.001). Arterial occlusion was more frequently observed in the KPSS ≥4 group (57.9 vs. 31.4%, p = 0.018). KPSS ≥4 was independently associated with administration of IV t-PA (odds ratio = 4.7; 95% confidence interval = 1.5-14.6, p = 0.008).
Reliable concordance between KPSS and NIHSS was found in acute stroke and TIA patients. KPSS ≥4 represents a good score to indicate prospective t-PA patients among those admitted within 3 h of stroke onset.
我们的目的是通过对可能适合静脉注射组织型纤溶酶原激活剂(IV t-PA)治疗的患者使用最高得分为 13 分的仓敷院前卒量表(KPSS),来证实急救人员使用该量表的效用。
研究对象为由急救人员转送至我院的急性卒中和短暂性脑缺血发作(TIA)患者。我们分析了 KPSS 与国立卫生研究院卒中量表(NIHSS)之间的相关性。将发病 3 小时内入院的患者分为 KPSS≥4 分和 KPSS<4 分两组。比较两组患者接受 IV t-PA 的比例。
在 430 例连续患者中(平均年龄 73 岁,男性 266 例),急救人员为 256 例患者记录了 KPSS 值(59.5%)。在所有 256 例患者(R=0.766;p<0.001)和 94 例发病 3 小时内入院的患者(急性缺血性卒中和 TIA,入院时有症状)(R=0.706;p<0.001)中,KPSS 与 NIHSS 之间均具有极好的相关性。在这 94 例患者中,KPSS≥4 分组(58 例患者中的 30 例,51.7%)比 KPSS<4 分组(36 例患者中的 5 例,13.9%)更频繁地接受 IV t-PA 治疗(p<0.001)。KPSS≥4 分组中动脉闭塞更为常见(57.9%比 31.4%,p=0.018)。KPSS≥4 与 IV t-PA 治疗独立相关(比值比=4.7;95%置信区间=1.5-14.6,p=0.008)。
在急性卒中和 TIA 患者中,KPSS 与 NIHSS 之间存在可靠的一致性。KPSS≥4 可作为发病 3 小时内入院的潜在 t-PA 患者的一个良好评分。