原发性血小板增多症：100例患者临床病程的回顾性研究
Essential thrombocythemia: a retrospective study on the clinical course of 100 patients.
作者信息
Chistolini A, Mazzucconi M G, Ferrari A, la Verde G, Ferrazza G, Dragoni F, Vitale A, Arcieri R, Mandelli F
机构信息
Dipartimento di Biopatologia Umana, Università La Sapienza, Roma, Italy.
出版信息
Haematologica. 1990 Nov-Dec;75(6):537-40.
We report a study concerning 100 patients affected by essential thrombocythemia: 90 adult (age greater than 20 years) and 10 pediatric subjects. The diagnosis was made by chance (78%), because of hemorrhages (10%), thrombosis (9%), vasomotor symptoms (29%). In the adult group, single-agent chemotherapy was performed with good remission using pipobroman or interferon. Antiaggregant agents were used in all patients at diagnosis. During the clinical course only a few complications occurred.
我们报告了一项关于100例原发性血小板增多症患者的研究：90例成人（年龄大于20岁）和10例儿科患者。诊断是偶然做出的（78%），因出血（10%）、血栓形成（9%）、血管舒缩症状（29%）。在成人组中，使用马利兰或干扰素进行单药化疗，缓解效果良好。所有患者在诊断时均使用了抗聚集剂。在临床过程中仅发生了少数并发症。
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