Bhan A, Das B, Venugopal P, Sampathkumar A, Chopra P
Department of Cardiothoracic and Vascular Surgery, AIIMS, New Delhi.
Indian Heart J. 1990 Nov-Dec;42(6):415-7.
Presence of Aschoff nodules and other chronic inflammatory cells in the left atrial appendage even in the absence of rheumatic activity has been reported in a high percentage of patients with chronic rheumatic valvular heart disease. This study was conducted on 37 left atrial appendages resected at the time of closed mitral valvotomy. Aschoff nodules were present in 61.2 percent of resected appendages, positivity being 71.4 percent in the age group of 20 years of less and 53.3 percent in patients more than 20 years of age. The histological findings did not change significantly in the presence of activity. The frequency of Aschoff nodules and chronic inflammatory cells and their subtypes also did not show any correlation with age, sex, duration of symptoms or severity of mitral stenosis.
即使在没有风湿活动的情况下，慢性风湿性心脏瓣膜病患者中也有很高比例被报道在左心耳存在Aschoff结节和其他慢性炎性细胞。本研究对37例二尖瓣闭式手术时切除的左心耳进行。切除的左心耳中61.2%存在Aschoff结节，20岁及以下年龄组阳性率为71.4%，20岁以上患者为53.3%。在有活动的情况下，组织学表现无明显变化。Aschoff结节和慢性炎性细胞及其亚型的频率也与年龄、性别、症状持续时间或二尖瓣狭窄严重程度无任何相关性。
