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[克拉科夫某工作场所特应性疾病发病率的初步评估]

[A preliminary assessment of the incidence of atopy at a workplace in Cracow].

作者信息

Jurczak W, Rysz A, Kopiński P, Podolec Z, Głuszko P

机构信息

Kliniki Alergii i Immunologii AM, Krakowie.

出版信息

Pol Tyg Lek. 1990;45(42-44):873-5.

PMID:2098735
Abstract

Skin tests, IgE level and eosinophils percentage were determined in 337 employees of the "Hydrokop" Works in Cracow. These investigations aimed at seeking more specific markers of allergy than anamnesis and skin tests. Allergy was reported by 108 individuals (38%). Some features of atopy were confirmed in 7.5%. Skin tests were positive in 36 individuals and were related to atopy in 55%. IgE levels were 10 IU/ml--greater than 1000 IU/ml with the distribution similar to log-normal. Mean IgE concentration was relatively high (202 IU/ml, in the individuals with confirmed congenital allergy. Percentage of eosinophils exceeded 3% in 39 subjects out of which 17 reported the symptoms of allergy. IgE level and percentage of eosinophils are controversial as the markers of atopy due to the contribution of various non-allergic factors while skin tests correlate well with allergic diseases which were relatively frequent in the examined group.

摘要

对克拉科夫“Hydrokop”工厂的337名员工进行了皮肤测试、免疫球蛋白E(IgE)水平和嗜酸性粒细胞百分比测定。这些调查旨在寻找比既往病史和皮肤测试更具特异性的过敏标志物。108人(38%)报告有过敏症状。7.5%的人证实有一些特应性特征。36人的皮肤测试呈阳性,其中55%与特应性有关。IgE水平为10国际单位/毫升至大于1000国际单位/毫升,其分布类似于对数正态分布。在确诊为先天性过敏的个体中,平均IgE浓度相对较高(202国际单位/毫升)。39名受试者的嗜酸性粒细胞百分比超过3%,其中17人报告有过敏症状。由于各种非过敏因素的影响,IgE水平和嗜酸性粒细胞百分比作为特应性标志物存在争议,而皮肤测试与受检组中相对常见的过敏性疾病相关性良好。

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