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[过敏家族史和特应性皮炎症状]

[Family history of allergy and symptoms of atopic dermatitis].

作者信息

Rudzki E, Litewska D, Samochocki Z, Rebandel P, Saciuk E, Chrupek A, Niemczyk B

机构信息

Kliniki Dermatologicznej AM, Warszawie.

出版信息

Pol Tyg Lek. 1990;45(42-44):876-9.

PMID:2098736
Abstract

Three hundred sixty five children and hundred thirty nine adults with atopic dermatitis were divided into three groups. Group A included patients with negative family history of allergy; group B--allergy history in one parent or his family; group C--allergy in both parents or their families. It was found that total IgE level was higher in patients of group C in comparison with group A. Similarly, bronchial asthma and/or rhinitis coexisted more frequently, incidence of urticaria was higher and its onset earlier in patients of group C. The results noted in patients of group B occupied middle position between those in group A and group C. Results related to the incidence of RAST positive reactions and multiple sensitivity were similar but the differences were lower. Radioimmunologic assays were performed only in part of the tested patients.

摘要

365名患有特应性皮炎的儿童和139名成人被分为三组。A组包括无过敏家族史的患者;B组——父母一方或其家族有过敏史;C组——父母双方或其家族有过敏史。结果发现,与A组相比,C组患者的总IgE水平更高。同样,支气管哮喘和/或鼻炎在C组患者中更频繁地共存,荨麻疹的发病率更高且发病更早。B组患者的结果介于A组和C组之间。与RAST阳性反应发生率和多重敏感性相关的结果相似,但差异较小。仅对部分受试患者进行了放射免疫测定。

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