Rudzki E, Litewska D, Samochocki Z, Rebandel P, Saciuk E, Niemczyk B
Pol Tyg Lek. 1990;45(42-44):880-2.
The study involved 117 adults and 535 children with atopic dermatitis. Immunoglobulins E against D. pteronyssinus--main allergen of the home dust--were assayed with RAST technique in children and FAST technique in adult patients. It was found that the blood serum IgE levels increase with patients' age and is the highest in patients with coexisting allergic respiratory diseases (difference statistically significant). RAST precision was compared with that of "prick" skin tests in the detection of allergy to home dust mites. Desensitization of 15 patients with home mite allergen produced satisfactory effects.
该研究涉及117名成人和535名患有特应性皮炎的儿童。采用RAST技术检测儿童针对屋尘主要过敏原——粉尘螨的免疫球蛋白E,采用FAST技术检测成年患者的该免疫球蛋白E。研究发现,血清IgE水平随患者年龄增加而升高,在合并过敏性呼吸道疾病的患者中最高(差异具有统计学意义)。比较了RAST检测对屋尘螨过敏的准确性与“点刺”皮肤试验的准确性。对15名对屋尘螨过敏原过敏的患者进行脱敏治疗,效果良好。