Bobrova I A, Khersonskaia R Ia, Rogotskaia L T
Vrach Delo. 1990 Nov(11):119-22.
The authors discuss the problem of widely spread chronic carrier state of HBs-antigen by healthy persons. The majority of antigen carriers show both moderate clinico-biochemical and ultrasonic signs of chronic liver involvement, and different disorders of the microcirculation which are formed in conditions of prolonged persistence of the virus of B hepatitis in the body. Early diagnosis of generalized disorders of the terminal blood circulation in antigen carriers may be useful in the determination of pathogenetically substantiated treatment tactics and prognostication of unfavourable outcomes of chronic HBs-antigen carrier state in preclinical period of the disease.
作者们讨论了健康人群中广泛存在的乙肝表面抗原慢性携带状态问题。大多数抗原携带者表现出慢性肝脏受累的中度临床生化和超声体征，以及在乙肝病毒长期持续存在于体内的情况下形成的不同微循环障碍。早期诊断抗原携带者终末血液循环的全身性障碍，对于确定基于发病机制的治疗策略以及预测疾病临床前期慢性乙肝表面抗原携带状态的不良结局可能是有用的。
