Antiparkinsonian activity and dopamine receptor binding studies of imidazolone derivatives.
作者信息
Naithani P K, Srivastava V K, Saxena A K, Barthwal J P, Gupta T K, Shanker K
机构信息
Department of Pharmacology and Therapeutics, King George's Medical College, Lucknow, India.
出版信息
Indian J Exp Biol. 1990 Dec;28(12):1145-8.
PMID:2099330
Abstract
Mannich bases and styryl derivatives of imidazolones were evaluated for their antiparkinsonian activity. Two compounds showed potent antiparkinsonian activity. These active compounds also showed binding with dopamine receptors in striatal membrane preparation of rat brain.
摘要
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