Guimarães Cabral L A
Facultade de Odontologia-UNESP.
Rev Odontol UNESP. 1990;19(1):125-39.
Histopathology by hematoxilin-eosin (HE) and periodic acid Schiff (PAS), concomitant direct immunofluorescence (DI) against total human immunoglobulins and against Candida albicans, was effectuated in 25 persons dentures wearers. In 5 persons without chronic athrofic candidiasis (CAC) clinical signals in the palate the HE showed wise inflammatory elements in the connective tissue and the PAS marked the continuous basal layer, the intra-cellular grains of granular layer and the uniform parakeratin on epithelial surface. In 20 others, with palatal signals of CAC, in the HE was frequent the features encountered in Candida infected and PAS revealed, beside descontinuous lamina basal and epithelial surface covered by tide and discontinuous parakeratin, the presence of round bodies few largers that presents in the granular layer, casually isolated in the medial portion of ret pegs and connective papillae. In the first 5 persons the DI against total human immunoglobulins not showed signals of the humoral immunologic phenomena, the same was valid to others 20 patients with CAC clinical aspects. However the DI with conjugate against C. albicans in the 20 cases with CAC signals revealed suitable aspects of the structures assumed by Candida in tissues. Cultures of samples obtained of the persons with CAC signals was positive in 100% to Candida, 70% presumptively albicans, against 80% of positiviness to generus Candida, 67% presumptively albicans, in the persons without CAC signals.
对25名戴假牙者进行了苏木精-伊红（HE）染色、过碘酸希夫（PAS）染色的组织病理学检查，并同时进行了针对总人类免疫球蛋白和白色念珠菌的直接免疫荧光（DI）检查。在5名腭部无慢性萎缩性念珠菌病（CAC）临床症状的患者中，HE染色显示结缔组织中有大量炎症成分，PAS染色标记了连续的基底层、颗粒层的细胞内颗粒以及上皮表面均匀的不全角化。在另外20名有腭部CAC症状的患者中，HE染色常见念珠菌感染的特征，PAS染色除了显示不连续的基底层和被潮状、不连续不全角化覆盖的上皮表面外，还显示在颗粒层有少数较大的圆形体，偶尔孤立于味蕾乳头和结缔乳头的内侧部分。在前5名患者中，针对总人类免疫球蛋白的DI未显示体液免疫现象的信号，其他20名有CAC临床表现的患者也是如此。然而，在20例有CAC症状的患者中，针对白色念珠菌的DI显示了念珠菌在组织中形成的结构的适当特征。有CAC症状患者的样本培养对念珠菌的阳性率为100%，推测白色念珠菌为70%，而无CAC症状患者对念珠菌属的阳性率为80%，推测白色念珠菌为67%。
