Isaac O, Thiemer K
Arzneimittelforschung. 1975 Sep;25(9):1352-4.
(--)-alpha-Bisabolol has a primary antipeptic action depending on dosage, which is not caused by an alteration of the pH-value. The proteolytic activity of pepsin is reduced by 50 percent through addition of bisabolol in the ratio of 1/0.5. The antipeptic action of bisabolol only occurs in case of direct contact. In case of a previous contact with the substrate, the inhibiting effect is lost.
(-)-α-红没药醇具有取决于剂量的主要抗胃蛋白酶作用,这并非由pH值的改变引起。通过以1/0.5的比例添加红没药醇,胃蛋白酶的蛋白水解活性降低50%。红没药醇的抗胃蛋白酶作用仅在直接接触的情况下发生。如果事先与底物接触,则抑制作用会丧失。