Schmidt J, Schmitt C, Hockwin O
Department of Experimental Ophthalmology, University of Bonn, FRG.
Lens Eye Toxic Res. 1990;7(3-4):643-50.
45 patients suffering from a primary hypercholesterolemia were treated with Simvastatin. Additionally to internal visits regular ophthalmologic examinations were performed. The main interest concerning the ophthalmologic examination was directed toward the documentation and measurement of lens opacities by means of Scheimpflug photography. Moreover, every 6 months a complete regular ophthalmologic examination was carried out. We present the results after a time period of 2 years. Relevant changes in clinical findings could not be found. In some patients the Scheimpflug measurement revealed an increase in light scattering. These findings, however, were within the limit of normal age related changes.
45名原发性高胆固醇血症患者接受了辛伐他汀治疗。除了门诊就诊外,还定期进行眼科检查。眼科检查的主要关注点是通过Scheimpflug摄影记录和测量晶状体混浊情况。此外,每6个月进行一次全面的常规眼科检查。我们呈现了2年时间段后的结果。未发现临床检查结果有相关变化。在一些患者中,Scheimpflug测量显示光散射增加。然而,这些发现属于正常年龄相关变化的范围。