Allen G I, Gilbert P F, Yin T C
Exp Brain Res. 1978 Jun 19;32(2):151-70. doi: 10.1007/BF00239724.
The patterns of convergence of inputs from different areas of the cerebral cortex and the peripheral nerves onto single dentate neurons was studied in cebus monkeys. Dentate neurons receive their strongest and most numerous inputs from the premotor and supplementary motor regions of area 6. The sensorimotor and frontal cortices have weaker projections to the dentate nucleus, while peripheral nerves and many other association cortical areas were found to be effective in influencing cells of the lateral cerebellum. Dentate cells that respond to stimulation of hindlimb regions of the sensorimotor cortex tend to receive their principal input from the supplementary motor area and medial premotor regions, while neurons responding to forelimb sensorimotor cortex tend to receive lateral premotor inputs. In addition there is a topographical organization within the ventral pole of dentate with the hindlimb represented in the anterior regions and the forelimb in the posterior regions. These results are compared with those of similar studies of interpositus and dentate neurons in cat and monkey. The differences between the afferent inputs to dentate and interpositus are consistent with the suggestion that the lateral cerebellum is involved in programming movement parameters before movement initiation while the intermediate zone is involved in up-dating the evolving movement.
在卷尾猴中研究了来自大脑皮层不同区域和外周神经的输入汇聚到单个齿状神经元上的模式。齿状神经元从6区的运动前区和辅助运动区接收最强且数量最多的输入。感觉运动皮层和额叶皮层向齿状核的投射较弱，而外周神经和许多其他联合皮层区域被发现对影响外侧小脑的细胞有效。对感觉运动皮层后肢区域刺激有反应的齿状细胞往往从辅助运动区和内侧运动前区接收主要输入，而对前肢感觉运动皮层有反应的神经元往往接收外侧运动前区的输入。此外，在齿状腹侧极内存在一种拓扑组织，后肢在前部区域代表，前肢在后部区域代表。将这些结果与在猫和猴中对间位核和齿状神经元的类似研究结果进行了比较。齿状核和间位核传入输入的差异与以下观点一致，即外侧小脑在运动开始前参与运动参数的编程，而中间区参与更新正在进行的运动。
