[软膏剂中泼尼松龙的测定]
[Determination of prednisolone in ointments].
作者信息
Heyde R, Schwalbe R, Illig G
机构信息
Apotheke des Bereiches Medizin, Martin-Luther-Universität Halle-Wittenberg.
出版信息
Pharmazie. 1990 Nov;45(11):860-1.
PMID:2100341
Abstract
A method for the quantitative determination of prednisolone in ointment preparations is described. It uses TLC and UV spectrophotometry in combination. Solutions and ointments are chromatographed using silica gel GF 254 and various solvent systems, the layers containing the active ingredient are eluted and the substance determined at 240 nm.
摘要
描述了一种测定软膏制剂中泼尼松龙含量的定量方法。该方法结合使用了薄层色谱法（TLC）和紫外分光光度法。使用硅胶GF 254和各种溶剂系统对溶液和软膏进行色谱分析，洗脱含有活性成分的层，并在240nm处测定该物质。
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