Berglund G
Department of Medicine, General Hospital, Malmö, Sweden.
Scand J Prim Health Care Suppl. 1990;1:67-71.
Diuretic drugs seem to be well tolerated during long-term antihypertensive treatment. Although they induce severe side effects necessitating withdrawal more often than placebo, the frequency of such withdrawals seem to be equal to that induced by beta-blocker treatment. The subjective tolerability as judged by questionnaires for symptoms and well being scores seems to indicate an over-all small improvement in patient well being. The effects in this respect seem to be similar to those exerted by a selective beta-blocker.
利尿药在长期抗高血压治疗期间似乎耐受性良好。虽然与安慰剂相比，它们更常引起严重副作用而需要停药，但此类停药的频率似乎与β受体阻滞剂治疗引起的频率相当。通过症状问卷和幸福感评分判断的主观耐受性似乎表明患者的整体幸福感略有改善。这方面的效果似乎与选择性β受体阻滞剂所产生的效果相似。
