Khoroshilova I P, Ilatovskaia L V, Bordiugova G G, Gakhramanov F S
Oftalmol Zh. 1990(6):358-62.
The paper generalizes and analyses experimental results obtained in 60 eyes of 30 rabbits after induced burn by means of epichlorhydrine that is widely used in chemical industry and produces industrial burns of the eye in 20% of all burns in the town of Sumgait. Clinico-morphologic researches allowed to reveal peculiarities of pathogenesis of severe eye burns produced by epichlorhydrine causing toxic lesions of the iris and to substantiate effectiveness of hordox used in such cases, that has not only antiproteolytic, but also antiinflammatory, cytotoxic action on the burn process.
该论文对30只家兔60只眼在使用环氧氯丙烷诱导烧伤后所获得的实验结果进行了归纳和分析。环氧氯丙烷在化学工业中广泛使用，在苏姆盖特市所有烧伤病例中，有20%是由其导致的眼部工业烧伤。临床形态学研究揭示了环氧氯丙烷所致严重眼烧伤的发病机制特点，这种烧伤会引起虹膜的毒性损伤，并证实了在此类病例中使用hordox的有效性，hordox不仅对烧伤过程具有抗蛋白水解作用，还具有抗炎和细胞毒性作用。
