Iroegbu C U, Njoku-Obi A N
Department of Microbiology, University of Nigeria, Nsukka.
Arch Roum Pathol Exp Microbiol. 1990 Jan-Mar;49(1):43-50.
Altogether 16,539 sputum specimens were examined microbiologically from 1980 to 1984. Out of these 12,588 were screened by Ziehl-Neelsen's staining technique and 782 were (6.3%) found AFB-positive. Age and sex distributions of the AFB-positive individuals were statistically significant (at 0.05), incidence being most prevalent among those 20 years and above (90.2%) and among males (61.2%). From other specimens cultured, non-AFB organisms were isolated at the following frequencies: coliform-like organisms (15.1%), Streptococcus pneumoniae (55.5%). Klebsiella pneumoniae (5.3%), Streptococcus pyogenes (3.9%), Pseudomonas aeruginosa (3.4%), Haemophilus influenzae (3.0%). Proteus Spp. (0.7%) and Escherichia coli (0.5%). The antibiogram of these isolates revealed a high incidence of multiple antibiotic resistance, a situation that has most probably arisen from the high degree of antibiotic misuse in Nigeria.
1980年至1984年期间，共对16539份痰标本进行了微生物学检查。其中12588份通过齐-尼染色技术进行筛查，发现782份（6.3%）抗酸杆菌阳性。抗酸杆菌阳性个体的年龄和性别分布具有统计学意义（P=0.05），发病率在20岁及以上人群中最高（90.2%），在男性中最高（61.2%）。从其他培养的标本中，以以下频率分离出非抗酸杆菌微生物：类大肠菌（15.1%）、肺炎链球菌（55.5%）、肺炎克雷伯菌（5.3%）、化脓性链球菌（3.9%）、铜绿假单胞菌（3.4%）、流感嗜血杆菌（3.0%）、变形杆菌属（0.7%）和大肠杆菌（0.5%）。这些分离株的抗菌谱显示多重耐药的发生率很高，这种情况很可能是由于尼日利亚抗生素滥用程度高所致。
