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巴利阿里群岛的红细胞酶多态性。II. 基于多变量分析的比较。

Red cell enzyme polymorphisms in the Balearic Islands. II. A comparison based on multivariate analyses.

作者信息

Miguel A, Castro J A, Ramon M M, Petitpierre E

机构信息

Departamento de Biologia, Facultad de Ciencies, Palma de Mallorca, Spain.

出版信息

Gene Geogr. 1990 Aug;4(2):89-98.

PMID:2101256
Abstract

A sample of 2143 individuals from Mallorca, coming from six geographic regions of this island: "Es Raiguer", "La Muntanya", "Es Plà", "Mijgorn", "Llevant" and "Palma", as well as 390 individuals from Eivissa island have been studied for the following six red cell enzyme systems: Esterase-D (ESD), acid phosphatase-1 (ACP1), glyoxalase-I (GLO1) 6-phosphogluconate dehydrogenase (PGD), phosphoglucomutase-1 (PGM1) and adenylate-kinase (AK1). The data were processed by means of multivariate statistical procedures: principal components, factorial correspondence and cluster analyses. The results indicate that ACP1 and ESD were the most suitable systems for the characterization of these caucasian populations, while GLO1 was important when different ethnic groups were included in the analyses. The Balearic gene frequencies fell within the European standard. Slight genetic distances were detected among the different Balearic populations, notably with the exception of the high differentiation of "La Muntanya".

摘要

对来自马略卡岛六个地理区域(“埃斯雷古埃尔”、“拉蒙塔尼亚”、“埃斯普拉”、“米乔恩”、“列万特”和“帕尔马”)的2143名个体以及来自伊维萨岛的390名个体进行了研究,涉及以下六种红细胞酶系统:酯酶-D(ESD)、酸性磷酸酶-1(ACP1)、乙二醛酶-I(GLO1)、6-磷酸葡萄糖酸脱氢酶(PGD)、磷酸葡萄糖变位酶-1(PGM1)和腺苷酸激酶(AK1)。数据通过多变量统计程序进行处理:主成分分析、因子对应分析和聚类分析。结果表明,ACP1和ESD是表征这些高加索人群最合适的系统,而当分析中纳入不同种族群体时,GLO1很重要。巴利阿里群岛的基因频率在欧洲标准范围内。在不同的巴利阿里群岛人群之间检测到了微小的遗传距离,特别是“拉蒙塔尼亚”的高度分化除外。

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