Efficient cell mediated lysis of human erythrocyte target cells is mediated by a human glycophorine A specific murine monoclonal antibody.

A human glycophorine A specific murine monoclonal antibody mediates the antibody dependent killing of antibody sensitized human erythrocytes by human K cells (monocyte-free mononuclear cells). The overall level of killing is lower than that mediated by conventional, human anti-D antibodies but it is significant on each target cell.