Deriugina E I, Drize N I, Lemeneva L N, Sadovnikova E Iu, Udalov G A, Chertkov I L
Sud Med Ekspert. 1990 Jan-Mar;33(1):35-7.
In this article serologic characteristics of monoclonal antibodies with anti-N specificity is given. Antibodies are directed to homologous sequence of N-form of A glycophorine (group-specific N-antigen) and B glycophorine, expressed both on N- and on M-erythrocytes. Higher titre and avidity of monoclonal antibodies with anti-N specificity in relation to erythrocytes with N-phenotype make it possible to detect N-antigen in material subjected to expert evaluation.
本文给出了具有抗-N特异性的单克隆抗体的血清学特征。这些抗体针对A血型糖蛋白N型(组特异性N抗原)和B血型糖蛋白的同源序列,在N型和M型红细胞上均有表达。具有抗-N特异性的单克隆抗体相对于N表型红细胞具有更高的效价和亲和力,这使得在进行专家评估的材料中检测N抗原成为可能。