人类带型染色体的显微切割与微克隆
Microdissection and microcloning of human banded chromosomes.
作者信息
Jonveaux P, Berger R
机构信息
INSERM U301, Institut de Génétique Moléculaire, Paris, France.
出版信息
Nouv Rev Fr Hematol (1978). 1990;32(6):455-7.
PMID:2101879
Abstract
A new microdissection and microcloning procedure of human banded chromosomes has been recently described. These microtechniques allow the construction of band-specific DNA libraries, providing a large number of DNA probes for the identification of gene sequences. These methodologies are particularly efficient to reach chromosomal regions involved in human genetic diseases including cancer.
摘要
最近描述了一种新的人类带型染色体显微切割和微克隆程序。这些微技术能够构建带特异性DNA文库，为基因序列的鉴定提供大量DNA探针。这些方法对于研究包括癌症在内的人类遗传疾病所涉及的染色体区域特别有效。
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