• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Synthesis of a new potent antitumor nucleoside, 2'-C-cyano-2'-deoxy-1-beta-D- arabinofuranosylcytosine.

作者信息

Matsuda A, Nakajima Y, Azuma A, Sasaki T, Ueda T

机构信息

Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.

出版信息

Nucleic Acids Symp Ser. 1990(22):51-2.

PMID:2101914
Abstract
摘要

相似文献

1
Synthesis of a new potent antitumor nucleoside, 2'-C-cyano-2'-deoxy-1-beta-D- arabinofuranosylcytosine.一种新型强效抗肿瘤核苷2'-C-氰基-2'-脱氧-1-β-D-阿拉伯呋喃糖基胞嘧啶的合成。
Nucleic Acids Symp Ser. 1990(22):51-2.
2
Synthesis of 4'-thio-beta-D-arabinofuranosylcytosine (4'-thio-ara-C) and comparison of its anticancer activity with that of ara-C.4'-硫代-β-D-阿拉伯呋喃糖基胞嘧啶(4'-硫代阿糖胞苷)的合成及其与阿糖胞苷抗癌活性的比较。
Nucleosides Nucleotides Nucleic Acids. 2000 Jan-Feb;19(1-2):329-40. doi: 10.1080/15257770008033012.
3
Nucleosides and nucleotides. 122. 2'-C-cyano-2'-deoxy-1-beta-D-arabinofuranosylcytosine and its derivatives. A new class of nucleoside with a broad antitumor spectrum.
J Med Chem. 1993 Dec 24;36(26):4183-9. doi: 10.1021/jm00078a006.
4
Nucleosides and nucleotides. 141. Chemical stability of a new antitumor nucleoside, 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine in alkaline medium: formation of 2'-C-cyano-2'-deoxy-1-beta-D-ribo-pentofuranosylcytosine and its antitumor activity.核苷与核苷酸。141. 一种新型抗肿瘤核苷2'-C-氰基-2'-脱氧-1-β-D-阿拉伯呋喃糖基胞嘧啶在碱性介质中的化学稳定性:2'-C-氰基-2'-脱氧-1-β-D-核糖呋喃糖基胞嘧啶的形成及其抗肿瘤活性。
J Med Chem. 1995 Aug 18;38(17):3391-7. doi: 10.1021/jm00017a023.
5
Synthesis and antitumor activity of 1-beta-4-selenoarabinofuranosyl cytosine (4'-seleno-ara-C).1-β-4-硒代阿拉伯呋喃糖基胞嘧啶(4'-硒代阿糖胞苷)的合成与抗肿瘤活性
Nucleic Acids Symp Ser (Oxf). 2008(52):639-40. doi: 10.1093/nass/nrn323.
6
Determinants in chemosensitivity of oncogene-transformed NIH3T3 cells to 2'-C-cyano-2'-deoxy-1-beta-D-arabinofuranosylcytosine.
Int J Oncol. 1999 Mar;14(3):543-9.
7
Formulation, stability, and antitumor activity of 1-beta-D-arabinofuranosylcytosine conjugate of thioether phospholipid.硫醚磷脂的1-β-D-阿拉伯呋喃糖基胞嘧啶共轭物的制剂、稳定性及抗肿瘤活性
Cancer Res. 1990 Jul 15;50(14):4401-6.
8
Antiproliferative activity and mechanism of action of fatty acid derivatives of arabinofuranosylcytosine in leukemia and solid tumor cell lines.阿糖胞苷脂肪酸衍生物在白血病和实体瘤细胞系中的抗增殖活性及作用机制
Biochem Pharmacol. 2004 Feb 1;67(3):503-11. doi: 10.1016/j.bcp.2003.09.028.
9
Synthesis and biological activity of 1-(2-deoxy-2-C-fluoromethyl- and 2-C-hydroxymethylarabinofuranosyl)-cytosines.
Nucleic Acids Symp Ser. 1993(29):33-4.
10
Nucleosides and nucleotides. 100. 2'-C-cyano-2'-deoxy-1-beta-D-arabinofuranosyl-cytosine (CNDAC): design of a potential mechanism-based DNA-strand-breaking antineoplastic nucleoside.核苷与核苷酸。100. 2'-C-氰基-2'-脱氧-1-β-D-阿拉伯呋喃糖基胞嘧啶(CNDAC):一种基于潜在机制的DNA链断裂抗肿瘤核苷的设计
J Med Chem. 1991 Sep;34(9):2917-9. doi: 10.1021/jm00113a034.