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Nucleosides and nucleotides. 100. 2'-C-cyano-2'-deoxy-1-beta-D-arabinofuranosyl-cytosine (CNDAC): design of a potential mechanism-based DNA-strand-breaking antineoplastic nucleoside.

作者信息

Matsuda A, Nakajima Y, Azuma A, Tanaka M, Sasaki T

机构信息

Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.

出版信息

J Med Chem. 1991 Sep;34(9):2917-9. doi: 10.1021/jm00113a034.

DOI:10.1021/jm00113a034
PMID:1895307
Abstract
摘要

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Nucleosides and nucleotides. 100. 2'-C-cyano-2'-deoxy-1-beta-D-arabinofuranosyl-cytosine (CNDAC): design of a potential mechanism-based DNA-strand-breaking antineoplastic nucleoside.核苷与核苷酸。100. 2'-C-氰基-2'-脱氧-1-β-D-阿拉伯呋喃糖基胞嘧啶（CNDAC）：一种基于潜在机制的DNA链断裂抗肿瘤核苷的设计
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[Design of a new antitumor nucleoside CNDAC, against solid tumors].
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