Itahara T, Koga S, Yoshitake T
Institute of Chemistry, College of Liberal Arts, Kagoshima University, Japan.
Nucleic Acids Symp Ser. 1990(22):9-10.
Treatment of 5-methylpyrimidine nucleosides and nucleotides with sodium peroxodisulfate in sodium phosphate buffer solution at pH 7.0 at 75 degrees C resulted in the selective oxidation of the methyl group. On the other hand, oxidation of thymidine by potassium peroxomonosulfate gave thymidine glycols.
在75℃、pH 7.0的磷酸钠缓冲溶液中，用过二硫酸钠处理5-甲基嘧啶核苷和核苷酸，甲基会发生选择性氧化。另一方面，过一硫酸钾氧化胸苷会生成胸苷二醇。
