苯并咪唑染料赫斯特8208与核酸的相互作用。
The interaction of the benzimidazole dye Hoechst 8208 with nucleic acids.
作者信息
Nakamura H, Hifumi H, Kubota Y
机构信息
Department of Chemistry, Faculty of Science, Yamaguchi University, Japan.
出版信息
Nucleic Acids Symp Ser. 1990(22):99-100.
PMID:2101927
Abstract
The interaction of Hoechst 8208 (H8208) with DNA and synthetic polynucleotides has been studied by absorption, fluorescence, flow dichroism, circular dichroism (CD), and viscosity measurements. The results are compatible with an intercalative mode of H8208 binding.
摘要
通过吸收光谱、荧光光谱、流动二色性、圆二色性（CD）和粘度测量等方法，研究了Hoechst 8208（H8208）与DNA及合成多核苷酸的相互作用。结果表明，H8208的结合模式符合嵌入模式。
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