Tormey W P
Department of Chemical Pathology, Beaumont Hospital, Dublin, Ireland.
Br J Clin Pract. 1990 Dec;44(12):582-4.
To devise a clinical laboratory policy for serum aldolase (ALD) requests, the use of ALD alone and in conjunction with serum creatine kinase (CK) was studied in 126 consecutive patients. Both enzymes were normal in 76 cases (60.3%); CK was normal but ALD was raised in 19 cases (15.1%); ALD was normal but CK raised in nine cases (7.1%); and both were raised in 16 (12.7%). The spectrum of disease was similar irrespective of the enzymes elevated. The role of ALD in the diagnosis and monitoring of muscle disease is in those cases where CK falls within the reference range.
为制定血清醛缩酶（ALD）检测申请的临床实验室政策，我们对126例连续患者单独使用ALD以及联合血清肌酸激酶（CK）进行了研究。两种酶均正常的有76例（60.3%）；CK正常但ALD升高的有19例（15.1%）；ALD正常但CK升高的有9例（7.1%）；两种酶均升高的有16例（12.7%）。无论哪种酶升高，疾病谱相似。在CK处于参考范围内的病例中，ALD在肌肉疾病的诊断和监测中发挥作用。
