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重症肌无力合并甲状腺毒症患者甲亢控制后的反应

Response to control of hyperthyroidism in patients with myasthenia gravis and thyrotoxicosis.

作者信息

Teoh R, Chow C C, Kay R, Cockram C S, McGuire L

机构信息

Department of Medicine, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin.

出版信息

Br J Clin Pract. 1990 Dec;44(12):742-4.

PMID:2102222
Abstract

Three patients presenting with both myasthenia gravis and thyrotoxicosis were treated initially with pyridostigmine and carbimazole respectively. Control of the hyperthyroidism was achieved in all cases but was accompanied by deterioration of the myasthenic symptoms in two and persistence in one. Thymectomy was performed with subsequent improvement in all three patients. Histology showed thymic hyperplasia in each case. The relationship of myasthenia gravis, thyrotoxicosis and the thymus is discussed.

摘要

三名同时患有重症肌无力和甲状腺毒症的患者,最初分别接受了吡啶斯的明和卡比马唑治疗。所有病例的甲状腺功能亢进均得到控制,但其中两例患者的重症肌无力症状恶化,一例患者症状持续存在。三名患者均接受了胸腺切除术,术后症状均有改善。组织学检查显示每例均有胸腺增生。本文讨论了重症肌无力、甲状腺毒症与胸腺之间的关系。

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