Bukumirović K
Institute of Public Health, Belgrade Ward of Epidemiology.
Srp Arh Celok Lek. 1990 Sep-Oct;118(9-10):393-6.
The paper deals with the epidemiological data on streptococcal diseases (pharyngitis, scarlet fever and rheumatic fever) over the period from 1981-1987. The results of epidemiological investigations revealed a continuous decrease of rheumatic fever in the population, aged from 0 to 19 years. The maximum mortality rate of streptococcal diseases was registered in 1982 with 4,259.59 cases of streptococcal pharyngitis, 544.08 cases of scarlet fever and 9.17 of rheumatic fever on 100,000 inhabitants. The minimum morbidity rate for rheumatic fever was registered in 1987 (3,31%). Over the period from 1976-1987 the morbidity rate of rheumatic fever was twice and four times decreased in the Belgrade population, aged 0-19 years. According to the conclusions of the Vith Republican Meeting on Rheumatic Fever (Belgrade, 1980) a success in primary prophylaxis of rheumatic fever was achieved. But, there are still some questions without answer, as for instance, what is the relation between the carrier and the risk of rheumatic fever; why the human alone is susceptible to rheumatic fever; is the immunisation a future alternative approach, ets. In view of current epidemiological data on rheumatic fever in the world, it is necessary to start with a longterm prospective epidemiological study to determine the prevalent M-types of group A streptococci directly related to rheumatic fever.
本文论述了1981年至1987年期间链球菌疾病（咽炎、猩红热和风湿热）的流行病学数据。流行病学调查结果显示，0至19岁人群中风湿热发病率持续下降。1982年记录的链球菌疾病死亡率最高，每10万居民中有4259.59例链球菌咽炎、544.08例猩红热和9.17例风湿热。1987年记录的风湿热发病率最低（3.31%）。在1976年至1987年期间，贝尔格莱德0至19岁人群中风湿热的发病率分别下降了两倍和四倍。根据第五届共和国风湿热会议（贝尔格莱德，1980年）的结论，风湿热的一级预防取得了成功。但是，仍有一些问题没有答案，例如，带菌者与风湿热风险之间的关系是什么；为什么只有人类易患风湿热；免疫接种是否是未来的替代方法等等。鉴于目前世界上关于风湿热的流行病学数据，有必要开展一项长期前瞻性流行病学研究，以确定与风湿热直接相关的A组链球菌流行M型。
