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耐甲氧西林金黄色葡萄球菌的噬菌体分型

Phage typing of methicillin-resistant Staphylococcus aureus.

作者信息

Abu Hanifah Y

机构信息

Department of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur.

出版信息

Malays J Pathol. 1990 Dec;12(2):107-9.

PMID:2102965
Abstract

448 isolates of methicillin-resistant Staphylococcus aureus (MRSA) from clinical specimens of patients from the University Hospital, Kuala Lumpur, were phage-typed. These included 35 strains causing two separate outbreaks of infection, one in surgical Ward 6B and another in the Special Care Nursery (SCN). Antibiograms of these outbreak strains in Ward 6B and SCN were entirely different. Phage-typing revealed that 72% of the MRSA isolates were typable. They were typed entirely by Group III phages, the majority (76%) of which were phage type 85. There was only one isolate in SCN which was typed by Group I (phage 80) and Group III phages. None were typed by phages 94, 95, 96 and Group II phages. 14.6% of the typable isolates gave the long pattern reaction of the phage 6/47/54/75/77/83A/84/85 complex. The majority of the outbreak strains in Ward 6B were of phage type 85, whereas those in the SCN were all of the 6/47/54/75/77/83A/84 phage pattern with the exception of one isolate which was also typed by phage 80, a Group I phage.

摘要

对来自吉隆坡大学医院患者临床标本的448株耐甲氧西林金黄色葡萄球菌(MRSA)进行了噬菌体分型。其中包括35株引起两起独立感染暴发的菌株,一起发生在外科6B病房,另一起发生在特别护理病房(SCN)。6B病房和SCN中这些暴发菌株的抗菌谱完全不同。噬菌体分型显示,72%的MRSA分离株可分型。它们完全由Ⅲ组噬菌体分型,其中大多数(76%)为85型噬菌体。SCN中只有一株由Ⅰ组(噬菌体80)和Ⅲ组噬菌体分型。没有分离株由94、95、96型噬菌体和Ⅱ组噬菌体分型。14.6%的可分型分离株出现了噬菌体6/47/54/75/77/83A/84/85复合体的长模式反应。6B病房中的大多数暴发菌株为85型噬菌体,而SCN中的暴发菌株除了一株也由Ⅰ组噬菌体80分型的分离株外,均为6/47/54/75/77/83A/84噬菌体模式。

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