Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, Michigan, USA.
J Cataract Refract Surg. 2010 Nov;36(11):1912-8. doi: 10.1016/j.jcrs.2010.09.003.
To compare the incidence of diffuse lamellar keratitis (DLK) after laser in situ keratomileusis (LASIK) with flap creation using the 15 kHz (FS15), 30 kHz (FS30), or 60 kHz (FS60) femtosecond laser.
University-based academic practice, Ann Arbor, Michigan, USA.
Retrospective comparative case series.
Consecutive myopic LASIK cases performed between January 1, 2005, and June 1, 2007, using the IntraLase FS15, FS30, or FS60 femtosecond laser for flap creation were reviewed. Preoperative clinical characteristics, treatment parameters, and intraoperative and postoperative complications were recorded. Statistical comparisons were made using repeated measures analysis, analysis of variance, chi-square, and Fisher exact tests.
Five hundred twenty eyes of 274 patients were included in the study. One hundred seventy-six eyes (93 patients) were treated with the FS15 laser, 180 eyes (93 patients) with the FS30 laser, and 164 eyes (89 patients) with the FS60 laser. Seventeen eyes (10%) in the FS15 laser group, 24 eyes (13%) in the FS30 laser group, and 23 eyes (14%) in the FS60 laser group developed DLK. There was no statistically significant difference in the incidence of DLK between the 3 groups (P = .68).
There was no significant difference in the incidence of DLK between the FS15, FS30, and FS60 groups.
比较使用 15 kHz（FS15）、30 kHz（FS30）或 60 kHz（FS60）飞秒激光制作角膜瓣的准分子激光原位角膜磨镶术（LASIK）后弥漫性层间角膜炎（DLK）的发生率。
美国密歇根州安阿伯市的一所大学附属医院。
回顾性对比病例系列研究。
回顾性分析了 2005 年 1 月 1 日至 2007 年 6 月 1 日期间使用 IntraLase FS15、FS30 或 FS60 飞秒激光行 LASIK 术的连续近视病例。记录术前临床特征、治疗参数、术中及术后并发症。采用重复测量分析、方差分析、卡方检验和 Fisher 确切概率法进行统计学比较。
共纳入 274 例患者的 520 只眼。其中 176 只眼（93 例）采用 FS15 激光治疗，180 只眼（93 例）采用 FS30 激光治疗，164 只眼（89 例）采用 FS60 激光治疗。FS15 激光组 17 只眼（10%）、FS30 激光组 24 只眼（13%）和 FS60 激光组 23 只眼（14%）发生 DLK。3 组间 DLK 的发生率无统计学差异（P=0.68）。
FS15、FS30 和 FS60 激光组间 DLK 的发生率无显著差异。
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