Han Eui Seok, Wee Won Ryang, Lee Jin Hak, Kim Mee Kum
Department of Ophthalmology, Seoul National University College of Medicine, Chongno-gu, Seoul, Korea.
Korean J Ophthalmol. 2007 Mar;21(1):6-10. doi: 10.3341/kjo.2007.21.1.6.
To evaluate visual outcome and the changes of contrast sensitivity (CS) after diffuse lamellar keratitis (DLK).
Using retrospective chart review, 48 eyes of 25 patients who underwent laser in situ keratomileusis (LASIK) with Visx S4 (VISX Inc., Santa Clara, CA) and M2 (Moria, France) and who were followed for at least six months were included. They were divided into two groups: DLK and non-DLK, by diagnosis of DLK or its absence after LASIK. Postoperative logMAR visual acuities and logCS measured using the VCTS 6500 (Vistech Consultants, Inc., Dayton, OH) were compared with preoperative values in the DLK and non-DLK groups at three and six months after LASIK.
There was no difference in logMAR visual acuity between the DLK and non-DLK groups until the sixth postoperative month. However, CS was significantly decreased at 12 and 18 cycle/degree compared with preoperative values (p=0.043 and p=0.045, respectively) in the DLK group, whereas CS was significantly increased at 12 cycle/degree in the non-DLK group (p=0.042) at six months.
DLK seemed to be strongly associated with a postoperative decrease of CS.
评估弥漫性层间角膜炎(DLK)后的视觉效果及对比敏感度(CS)变化。
采用回顾性病历审查,纳入25例接受威视S4(VISX公司,加利福尼亚州圣克拉拉)和M2(法国摩里亚)准分子原位角膜磨镶术(LASIK)且随访至少6个月的患者的48只眼。根据LASIK术后是否诊断为DLK将其分为两组:DLK组和非DLK组。比较LASIK术后3个月和6个月时,DLK组和非DLK组的术后对数最小分辨角视力(logMAR)及使用VCTS 6500(Vistech咨询公司,俄亥俄州代顿)测量的对数对比敏感度(logCS)与术前值。
术后第6个月前,DLK组和非DLK组的logMAR视力无差异。然而,DLK组在术后6个月时,12和18周/度的CS与术前值相比显著降低(分别为p = 0.043和p = 0.045),而非DLK组在12周/度时CS显著升高(p = 0.042)。
DLK似乎与术后CS降低密切相关。