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非那雄胺与男性乳腺癌:药品和健康产品管理局的报告显示存在关联吗?

Finasteride and Male Breast Cancer: Does the MHRA Report Show a Link?

作者信息

Shenoy Niraj K, Prabhakar Sangolli M

机构信息

#301-B, Ranka Colony, Bilekahalli, Bannerghatta Road, Bangalore - 560 076, India.

出版信息

J Cutan Aesthet Surg. 2010 May;3(2):102-5. doi: 10.4103/0974-2077.69022.

Abstract

Finasteride is an important drug for the management of androgenetic alopecia. However, there are concerns about the possible side effects of the drug such as impotence. Recently stray reports have appeared about the occurrence of male breast carcinoma in patients who received the drug. These have been looked in to by Medicines and Health care products Regulatory Agency (MHRA). This article summarizes the MHRA report.

摘要

非那雄胺是治疗雄激素性脱发的一种重要药物。然而,人们担心该药物可能存在副作用,如阳痿。最近,有关于接受该药物治疗的患者发生男性乳腺癌的零星报道。药品和保健品管理局(MHRA)已对此进行了调查。本文总结了MHRA的报告。

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本文引用的文献

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Male breast cancer.男性乳腺癌
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Epidemiology of male breast cancer.男性乳腺癌的流行病学
Cancer Epidemiol Biomarkers Prev. 2005 Jan;14(1):20-6.
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Finasteride in benign prostatic hyperplasia.
N Engl J Med. 2004 Mar 25;350(13):1359-61; author reply 1359-61. doi: 10.1056/NEJMc045013.
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Is male breast cancer similar or different than female breast cancer?男性乳腺癌与女性乳腺癌相似还是不同?
Breast Cancer Res Treat. 2004 Jan;83(1):77-86. doi: 10.1023/B:BREA.0000010701.08825.2d.
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Male breast cancer during finasteride therapy.非那雄胺治疗期间发生的男性乳腺癌。
J Natl Cancer Inst. 2004 Feb 18;96(4):338-9. doi: 10.1093/jnci/djh062.

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