Torres-Sánchez Luisa, López-Carrillo Lizbeth
Instituto Nacional de Salud Pública, Cuernavaca, Morelos, México.
Salud Publica Mex. 2010 Sep-Oct;52(5):461-7. doi: 10.1590/s0036-36342010000500014.
Fumonisins are mycotoxins that contaminate maize, disrupt the folate and sphingolipid metabolism, are associated with neural tube defects, and are considered by the International Agency for Research on Cancer (IARC) as possible human carcinogens. Since maize-based foods are significant components of the Mexican diet and there is a high prevalence of genetic susceptibility for folate deficiency among Mexicans, this essay presents international and national evidence of fumonisin exposure and the relevance that such exposure represents for Mexico.
伏马菌素是一种污染玉米的霉菌毒素，它会扰乱叶酸和鞘脂代谢，与神经管缺陷有关，国际癌症研究机构（IARC）认为它可能是人类致癌物。由于以玉米为基础的食品是墨西哥饮食的重要组成部分，而且墨西哥人叶酸缺乏的遗传易感性普遍较高，因此本文展示了伏马菌素暴露的国际和国内证据，以及这种暴露对墨西哥的相关性。
