Edmonson Peter, Stubbs Desmond, Hunt William
Zen Sensing LLC., Decatur, GA, USA.
Methods Mol Biol. 2011;692:83-100. doi: 10.1007/978-1-60761-971-0_7.
The detection of bacterial signaling molecules in liquid or gaseous environments has been occurring in nature for billions of years. More recently, man-made materials and systems has also allowed for the detection of small molecules in liquid or gaseous environments. This chapter will outline some examples of these man-made detection systems by detailing several acoustic-wave sensor systems applicable to quorum sensing. More importantly though, a comparison will be made between existing bacterial quorum sensing signaling systems, such as the Vibrio harveyi two-component system and that of man-made detection systems, such as acoustic-wave sensor systems and digital communication receivers similar to those used in simple cell phone technology. It will be demonstrated that the system block diagrams for either bacterial quorum sensing systems or man-made detection systems are all very similar, and that the established modeling techniques for digital communications and acoustic-wave sensors can also be transformed to quorum sensing systems.
在液体或气体环境中检测细菌信号分子在自然界已经存在了数十亿年。最近，人造材料和系统也能够在液体或气体环境中检测小分子。本章将通过详细介绍几种适用于群体感应的声波传感器系统，概述这些人造检测系统的一些示例。然而，更重要的是，将对现有的细菌群体感应信号系统（如哈氏弧菌双组分系统）与类似简单手机技术中使用的人造检测系统（如声波传感器系统和数字通信接收器）进行比较。结果将表明，细菌群体感应系统或人造检测系统的系统框图都非常相似，并且数字通信和声波传感器的既定建模技术也可以转化为群体感应系统。
