Kriett J M, Tarazi R Y, Kaye M P
University of California, San Diego.
Clin Transpl. 1990:21-7.
As of October 1990, the Registry of the International Society for Heart Transplantation has received data on over 14,000 heart and over 1,100 combined heart-lung or lung transplant recipients from over 200 centers worldwide. While the areas of single-lung transplantation and pediatric heart transplantation continue to expand rapidly, further growth in annual numbers of cardiac and pulmonary transplant procedures is now limited by donor supply. Operative mortality and late survival have improved during the past decade, however, infection and rejection continue to be the main causes of death. As the number of long-term survivors continues to increase, chronic rejection remains the major obstacle and results with retransplantation have not been very encouraging.
截至1990年10月，国际心脏移植学会登记处已收到来自全球200多个中心的14000多例心脏移植以及1100多例心肺联合或肺移植受者的数据。虽然单肺移植和小儿心脏移植领域仍在迅速扩展，但目前心脏和肺移植手术年度数量的进一步增长受到供体供应的限制。在过去十年中，手术死亡率和远期生存率有所改善，然而，感染和排斥反应仍然是主要的死亡原因。随着长期存活者数量持续增加，慢性排斥反应仍是主要障碍，再次移植的结果并不十分令人鼓舞。
