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始于樟脑——日本精细化学的发展历程

[Starting with camphor--the progress of Nippon Fine Chemical].

作者信息

Kimura Osamu

机构信息

The Kinki Chemical Society, Japan, 4-10-1-1218 Shibaura, Minato-ku, Tokyo 108-0023.

出版信息

Yakushigaku Zasshi. 2010;45(1):71-7.

PMID:21032891
Abstract

In 1918, Nippon Fine Chemical Co., Ltd. (NFC) was founded under the name, Nippon Camphor Co., Ltd. for the purpose of unifying the camphor business throughout Japan. The company manufactured purified camphor as a government-monopolized good. Camphor was used as a plasticizer for nitrocellulose, as a moth repellent, as an antimicrobial substance, as a rust inhibitor, and as an active ingredient in medicine. It was also a very important good exported in order to obtain foreign currency. Later on, after World War II and the abolition of the camphor monopoly, the company started manufacturing products related to oils and fats, including higher fatty acids, and expanded its business by developing a new field of chemical industry. In 1971 the company changed its name to Nippon Fine Chemical Co., Ltd., and made a new start as a diversified fine chemicals company. Recently, the fine chemicals division of NFC has concentrated on rather complex molecules, such as active pharmaceutical ingredients, and other chemicals. Since 2000, NFC have started to supply "Presome", precursors of liposome DDS drugs. NFC is strengthening marketing strategies in foreign countries with unique technologies and products.

摘要

1918年,日本精细化学有限公司(NFC)以日本樟脑有限公司的名义成立,目的是统一全日本的樟脑业务。该公司生产作为政府专卖商品的精制樟脑。樟脑被用作硝酸纤维素的增塑剂、驱虫剂、抗菌物质、防锈剂以及药物中的活性成分。它也是一种非常重要的用于获取外汇的出口商品。后来,二战后樟脑专卖制度被废除,该公司开始生产与油脂相关的产品,包括高级脂肪酸,并通过开拓新的化学工业领域来扩大业务。1971年,公司更名为日本精细化学有限公司,作为一家多元化的精细化学品公司重新起步。最近,NFC的精细化学品部门专注于生产更为复杂的分子,如活性药物成分及其他化学品。自2000年以来,NFC开始供应“Presome”,即脂质体药物递送系统(DDS)药物的前体。NFC正在凭借独特的技术和产品加强在国外的营销策略。

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